[resoluteteeth]

The thing is, even people who are obese and gaining weight over time are usually just eating a tiny calorie surplus each day.

If people take GLP-1 meds and get down into the normal range, at that point even if they stay on the drugs, they're going to have to adjust the dose so they stop losing weight again (without gaining weight).

This means that even if everyone who's overweight or obese started taking GLP-1 drugs and started losing weight right now, the reduction in food consumption would still be limited and short term.

So I think this concern is somewhat overblown.

[gedy]

They really don't seem to work that way, it's not a calorie minusing weight loss pill.

[resoluteteeth]

They don't work by reducing appetite, causing people to eat less? What mechanism do you think they work by then?