[tsol]

Parasites used to be ubiquitous before we had medication to kill them. There's even a (not very well supported) theory that these parasites helped with allergies by moderating immune system. They releasing chemicals to lower immune activity in order to protect themselves, so the idea that we had these for thousands of years and basically are made to have them is intriguing. It's called "helminthic therapy" and it's considered alternative medicine but there is some academic interest. Results in clinical trials have been mixed. Perhaps the future is just synthetic hookworm proteins that regulate your immune system as our ancestors once had.

[IneffablePigeon]

My partner researches one parasite named in this study (a type of whipworm) and they actually get their eggs for in vitro work from another researcher abroad who infected himself with the parasite because he finds it helps with his autoimmune disease. He harvests the eggs and distributes them to other teams.

[pazimzadeh]

That makes sense because to an extent the immune system can’t walk and chew gum at the same time. Immune cells often get polarized to either type 1 (viruses, cancer, autoimmunity) or type 2 (parasites, worms, toxins) immune responses but not both. So he’s effectively distracting his immune system.

[culi]

Scientists that study mosquitoes in a lab will commonly feed the mosquitoes with their own blood. Literally sticking their arm in and letting them feed.

https://www.theguardian.com/australia-news/2025/jun/23/mosqu...

[thaumasiotes]

There is a significantly more mainstream but similar-in-the-broad-strokes theory, the Hygiene Hypothesis, which says that the immune system relies on encountering things like this for calibration, but doesn't require them as a continual presence for optimal functioning.

[andy99]

Intuitively it wouldn’t be surprising that there’s some symbiosis going on somewhere and that there would be beneficial parasites. In reality I have no idea.

[morkalork]

Jaffa Kree?

[nephihaha]

Skin mites are fairly beneficial.

[patmorgan23]

Doesn't seem too off from gut micro biome theories.

[wtcactus]

I would argue that parasites only became ubiquitous when we abandoned our hunter gatherers way of life and settled into agricultural communities of larger scale (something relatively recent when compared to human evolution).

So, I doubt that immune system theory, since for most of mankind’s existence, they were not part of our life.

[thaumasiotes]

Your argument is total nonsense. Parasites are ubiquitous in all animals, and plants, right now, today. When did they abandon their hunter-gatherer way of life?

> for most of mankind’s existence, [parasites] were not part of our life.

This is not something you should have been able to say with a straight face. It proves nothing other than that nobody should ever take you seriously.

[throwaway5465]

The average body temperature then was also higher.

[ape4]

How could that be observed?