[squirrel]

It seems you are assuming that because the majority of people have a certain quantity of glutamate receptors, that they are the healthy ones and that we should be trying to bring autistic people up to that level. Is that right?

Why not consider the opposite, that the most beneficial quantity of glutamate receptors could be somewhere below the typical amount? If that were true, then we could try to help others reduce their glutamate receptor level to become healthier and more successful (and a little more autistic).

If we found, say, an association between a lower level of neurological characteristic X and concert-level piano skill, then those who aspire to play that instrument at an elite level might try to decrease X. The fact that most of us are rubbish piano players would not be evidence that lower levels of X are harmful, but very much the opposite.

[delis-thumbs-7e]

It is an interesting idea, but let’s not assume autistic traits make you more talented in anything. There certainly is very highly intelligent people with autistic traits that are able to use hyper-focusing to help them work very hard and succeed in academia or at work. I doubt any rational person is looking for ”a cure” for the Alan Turings and Albert Einsteins of this world. Nor even for a regular, albeit slightly odd, chap like myself, who likes reading books alone with his cat and studying math instead of seeing other people.

However there are people with severe autism that makes it more or less impossible for them to communicate with other people or live independently. If these people could have their life improved it might make huge difference to them and their families.

[mystraline]

> All autistic participants in the study had average or above average cognitive abilities. McPartland and collaborators are also working together on developing other approaches to PET scans that will enable them to include individuals with intellectual disabilities in future studies.

Simply put they didn't even touch the keeners, nonverbalists, the piss-in-your-pants, or the perpetual 1 year old autistics. They went after people who previously would be called "Aspergers syndrome".

But everything cognitive seems to be called 'autism spectrum disorder' these days.

[ggm]

You're absolutely right that assumption was implicit. The answer was written totally in that framework. I'm not here to say what's right or wrong in determining something about people who lie outside of normal in these things, or what normal means.

So what I wrote should be read with a "if it is held to be a condition which deserved remediation or avoidance of it's manifestation" attached.

Most medical conditions are couched in this sense, that a deficit or departure from the normal is a problem. In matters of brain chemistry it pays to be more nuanced.