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DuckDB is an open-source column-oriented Relational Database Management System (RDBMS). It's designed to provide high performance on complex queries against large databases in embedded configuration.

It has transparent compression built-in and has support for natural language queries. https://buckenhofer.com/2025/11/agentic-ai-with-duckdb-and-s...

"DICT FSST (Dictionary FSST) represents a hybrid compression technique that combines the benefits of Dictionary Encoding with the string-level compression capabilities of FSST. This approach was implemented and integrated into DuckDB as part of ongoing efforts to optimize string storage and processing performance." https://homepages.cwi.nl/~boncz/msc/2025-YanLannaAlexandre.p...