[matthewmacleod]

I mean… https://pubmed.ncbi.nlm.nih.gov/40934115/

A total of 205 participants were randomly assigned to receive oral semaglutide, and 102 to receive placebo. The estimated mean change in body weight from baseline to week 64 was -13.6% in the oral semaglutide group and -2.2% in the placebo group (estimated difference, -11.4 percentage points; 95% confidence interval, -13.9 to -9.0; P<0.001).

At what would be $10/day – why's that ineffective?

[Someone1234]

Because if you compare it to the injection trial, you'll see even higher weight loss, and even lower side effects. We're also producing 25mg of oral medication for the same effectiveness as 2.4mg of injection; that doesn't make economic sense.

[JumpCrisscross]

> We're also producing 25mg of oral medication for the same effectiveness as 2.4mg of injection; that doesn't make economic sense

Plenty of people can’t or won’t inject. And plenty of people don’t need 2.4mg injected.

The pill is cheaper to make, distribute and take. That seems to make economic sense to me.