Brad Marshall[0] makes a case for the benefits of stearic acid (C18:0), which is predominant in beef tallow and cocoa butter. It acts as a beneficial metabolic signal that promotes mitochondrial fat oxidation, higher energy expenditure, and leanness—counteracting the obesogenic effects of polyunsaturated fats (PUFAs), especially linoleic acid.[0] https://fireinabottle.net/every-fire-in-a-bottle-post-from-t...
EDIT: I'm sympathetic to Brad's argument and I'm concerned that RFK Jr's incompetence will interfere with ongoing research in this area of metabolism.
bloaf|1 month ago
However, the problem is that the public has also come to that conclusion. The public has gone on to decide "that means my incredibly weakly-evidenced idea is just as good as the expert opinions" which does not follow and is often disastrously wrong.
So I'm also sympathetic to the idea that the saturated fat picture is more complex than a blanket ban suggests. But I know better than to treat things like Brad's arguments as anything other than "interesting hypothesis" as opposed to "something we actually know about nutrition."
graemep|1 month ago
The public are presented with things that are weakly evidenced as scientifically proven. After all, the one study that says something is good or bad for you was published in a peer-reviewed journal and the university PR people blogged about it and the newspapers reported it uncritically.
A lot of experts are very bad at differing between different levels of evidence and probability: "my personal (if expert) opinion", "a consensus in the field" and "backed by reasonable evidence" and "proven" are very different but all often get presented the same way.
franktankbank|1 month ago
Noaidi|1 month ago
Does Brad Marshall mention that Palmitic acid is the dominant fatty acid in tallow? And since Palmitic acid is the most abundant SFA in the U.S. diet, can we draw a conclusion that it may partially play a role in poor health outcomes?
PUFA suppress lipogenic gene expression so I do not know where anyone is getting that polyunsaturated fats have and obesogenic effect. [1]
[1] https://www.nature.com/articles/s41467-025-65613-2
pc86|1 month ago