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getpost | 1 month ago

Brad Marshall[0] makes a case for the benefits of stearic acid (C18:0), which is predominant in beef tallow and cocoa butter. It acts as a beneficial metabolic signal that promotes mitochondrial fat oxidation, higher energy expenditure, and leanness—counteracting the obesogenic effects of polyunsaturated fats (PUFAs), especially linoleic acid.

[0] https://fireinabottle.net/every-fire-in-a-bottle-post-from-t...

EDIT: I'm sympathetic to Brad's argument and I'm concerned that RFK Jr's incompetence will interfere with ongoing research in this area of metabolism.

discuss

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bloaf|1 month ago

We all know there has been a replication crisis across many different disciplines of science. I think that the set of things we actually know about nutrition and health is a lot smaller than the experts think.

However, the problem is that the public has also come to that conclusion. The public has gone on to decide "that means my incredibly weakly-evidenced idea is just as good as the expert opinions" which does not follow and is often disastrously wrong.

So I'm also sympathetic to the idea that the saturated fat picture is more complex than a blanket ban suggests. But I know better than to treat things like Brad's arguments as anything other than "interesting hypothesis" as opposed to "something we actually know about nutrition."

graemep|1 month ago

I think the experts and the media are to blame.

The public are presented with things that are weakly evidenced as scientifically proven. After all, the one study that says something is good or bad for you was published in a peer-reviewed journal and the university PR people blogged about it and the newspapers reported it uncritically.

A lot of experts are very bad at differing between different levels of evidence and probability: "my personal (if expert) opinion", "a consensus in the field" and "backed by reasonable evidence" and "proven" are very different but all often get presented the same way.

franktankbank|1 month ago

Lived experience is not really weak evidence though. Personally I use tallow minimally but it seems like a really good high flash point oil.

Noaidi|1 month ago

Taking one fatty acid out of a complex fat like tallow and therefore extrapolating that "tallow is good for you and everyone" is a huge mistake.

Does Brad Marshall mention that Palmitic acid is the dominant fatty acid in tallow? And since Palmitic acid is the most abundant SFA in the U.S. diet, can we draw a conclusion that it may partially play a role in poor health outcomes?

PUFA suppress lipogenic gene expression so I do not know where anyone is getting that polyunsaturated fats have and obesogenic effect. [1]

[1] https://www.nature.com/articles/s41467-025-65613-2

pc86|1 month ago

Fallacy of composition. It does not logically follow that given Palmitic acid is the most abundant SFA in the US diet (objectively true), and given the US diet directly leads to poor health outcomes (very likely but not proven at least not to the level of the prior claim), that Palmitic acid contributes to poor health outcomes. It's entirely possible Palmitic acid is great for you and if we had less we'd be doing even worse. The statements are simply not connected at all.