[theothertimcook]

The XR mechanism is shit compared how vyvanse and concerts manage theirs.

If you’re a slow metaboliser you end up getting a big overlap around 3hours in which can be quite unpleasant, hence the non XR compound

[InMice]

If I take the lowest dose concerta I will not sleep that night no matter how early i take it. This was pretty devestating when I was younger and not mature enough to realize what was going on. Parents were obsessed with ADD medication at the time. I think vyvanse or xr adderall would be a similar nightmare for me.

[theothertimcook]

Interesting.

I had similar issues with XR methylphenidate and Dex, but concerta and vyvanse were find if I took them first thing.

I suspect a bit insignificant amount of people are slow metabolisers and are having a shit run with stimulants as a result