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blakesterz | 1 month ago

Of course, why are the good ones always in mice?

  A study led by Stanford Medicine researchers has found that an injection blocking a protein linked to aging can reverse the natural loss of knee cartilage in older mice.

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agumonkey|1 month ago

I guess we should pay scientist to look into the human-to-mice transformation problem

LoveMortuus|1 month ago

I would love that, as long as the lifespan didn't change. If everyone turned into mice we'd have a lot more space for other stuff, we'd need less food, less resources in general, since we'd be physically smaller, this thought is one of the reasons I like the movie arthur and the minimoys, where the main character gets shrunk to like 2mm in size!

random3|1 month ago

This :))) or the other way around

trebligdivad|1 month ago

It's all that wheel running, terrible on the knees.

abdullahkhalids|1 month ago

If only a small percentage of studies make it past the mice stage to be tested on humans, it means that a lot more studies have been done on mice than humans. Hence, we know more about mouse biology than human biology. So over time, it must get easier and easier to generate positive results in mice, which are uncorrelated with the success in humans.

spwa4|1 month ago

It's worse than that. People get to interfere in mice. You can stunt their growth, give them transparent skin, grow more or less limbs, cut into them ... you can't experiment at all on humans.

Especially when it comes to pregnancies we know more about a lot of animals than about humans. Why? Well pregnancies is how you multiply meat in animals, which is what farmers are interested in (and pay for). Which ironically also means animal pregnancies can be treated in case of trouble much more effectively.

Why pregnancies? Pregnancy changes a LOT of chemical processes in the body and so quite a bit of "normal" medical knowledge doesn't apply to pregnant women. Which has caused the medical establishment to declare anything that isn't explicitly tested on pregnant women as a no-go zone. So even problems and medications that we do know about, doctors won't apply them to pregnant women.

irishcoffee|1 month ago

Douglas Adams continues to be ahead of his time.

laughing_man|1 month ago

Mice have the best medical care. Maybe Douglas Adams was right.

On a serious note, it seems like a whole lot of drugs work great on mice and not so much on people.

worthless-trash|1 month ago

I imagine because mice dont misbehave, lie about taking the drugs, get enough sleep, eat consistently and dont have to take other drugs masking complex interactions.

AnimalMuppet|1 month ago

It's because Mickey Mouse has enough money to fund a lot of medical research, and he's not stingy.

seydor|1 month ago

We live in the Matrix, and Mice are the overlords.

IAmBroom|1 month ago

"A chemical is something that causes cancer in lab mice."

By analogy, "A drug is something that cures cancer in lab mice."