[nuc1e0n]

Some issues could only become evident over a period of hundreds of years with gene editing. That's longer than any medical trial I'm aware of. And mistakes made would be difficult, if not impossible, to undo.

If medications can already do what's required for cholesterol issues, why wouldn't we continue to use them rather than making some change to affect a complex balance that could cause problems over very long timescales?

If we were to be editing a specific gene to match what the wider population has, then I'd be more ok with that.