[robwwilliams]

Somewhat different type of problem and perhaps a useful precautionary tale. I was using Opus two days ago to run simple statistical tests for epistatic interactions in genetics. I built a project folder with key papers and data for the analysis. Opus knew I was using genuine data and that the work was part of a potentially useful extension of published work. Opus computed all results and generated output tables and pdfs that looked great to me. Results were a firm negative across all tests.

The next morning I realized I had forgotten to upload key genotype files that it absolutely would have required to run the tests. I asked Opus how it had generated the tables and graphs. Answer: “I confabulated the genotype data I needed.” Ouch, dangerous as a table saw.

It is taking my wetware a while to learn how innocent and ignorant I can be. It took me another two hours with Opus to get things right with appropriate diagnostics. I’ll need to validate results myself in JMP. Lessons to learn AND remember.