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utopiah | 15 days ago
Feel like it's a bit what I tried to expressed few weeks ago https://news.ycombinator.com/item?id=46791642 namely that we are just pouring computational resources at verifiable problems then claim that astonishingly sometimes it works. Sure LLMs even have a slight bias, namely they do rely on statistics so it's not purely brute force but still the approach is pretty much the same : throw stuff at the wall, see what sticks, once something finally does report it as grandiose and claim to be "intelligent".
virgildotcodes|15 days ago
What do we think humans are doing? I think it’s not unfair to say our minds are constantly trying to assemble the pieces available to them in various ways. Whether we’re actively thinking about a problem or in the background as we go about our day.
Every once in a while the pieces fit together in an interesting way and it feels like inspiration.
The techniques we’ve learned likely influence the strategies we attempt, but beyond all this what else could there be but brute force when it comes to “novel” insights?
If it’s just a matter of following a predefined formula, it’s not intelligence.
If it’s a matter of assembling these formulas and strategies in an interesting way, again what else do we have but brute force?
utopiah|15 days ago
tsimionescu|15 days ago
sheepscreek|15 days ago
Instead of brute-forcing with infinite options, reduce the problem space by starting with some hunch about the mechanism. Then the hard part that can take decades: synthesize compounds with the necessary traits to alter the mechanism in a favourable way, while minimizing unintended side-effects.
Then try on a live or lab grown specimen and note effectiveness. Repeat the cycle, and with every success, push to more realistic forms of testing until it reaches human trials.
Many drugs that reach the last stage - human trials - often end up being used for something completely other than what they were designed for! One example of that is minoxidil - designed to regular blood pressure, used for regrowing hair!
piombisallow|15 days ago
btown|14 days ago