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virgildotcodes | 16 days ago
What do we think humans are doing? I think it’s not unfair to say our minds are constantly trying to assemble the pieces available to them in various ways. Whether we’re actively thinking about a problem or in the background as we go about our day.
Every once in a while the pieces fit together in an interesting way and it feels like inspiration.
The techniques we’ve learned likely influence the strategies we attempt, but beyond all this what else could there be but brute force when it comes to “novel” insights?
If it’s just a matter of following a predefined formula, it’s not intelligence.
If it’s a matter of assembling these formulas and strategies in an interesting way, again what else do we have but brute force?
utopiah|16 days ago
virgildotcodes|16 days ago
How many people have tried to figure out a new maths, a GUT in physics, a more perfect human language (Esperanto for ex.) or programming language, only to fail in the vast majority of their attempts?
Do we think that anything but the majority of the attempts at a paradigm shift will end in failure?
If the majority end in failure, how is that not the same brute force methodology (brute force doesn’t mean you can’t respond to feedback from your failed experiments or from failures in the prevailing paradigms, I take it to just fundamentally mean trying “new” things with tools and information available to you, with the majority of attempts ending in failure, until something clicks, or doesn’t and you give up).
tsimionescu|16 days ago
adgjlsfhk1|15 days ago
gus_massa|16 days ago
Method A) 30% speed reduction and 80% precision decrease
Method B) 50% speed reduction and 5% precision increase
Method C) 740% speed reduction and 1% precision increase
and we only publish B. It's not brute force[1], but throw noodles at the wall, see what sticks, like the GP said. We don't throw spoons[1], but everything that looks like a noodle has a high chance of been thrown. It's a mix of experience[1] and not enough time to try everything.
[1] citation needed :)
sheepscreek|16 days ago
Instead of brute-forcing with infinite options, reduce the problem space by starting with some hunch about the mechanism. Then the hard part that can take decades: synthesize compounds with the necessary traits to alter the mechanism in a favourable way, while minimizing unintended side-effects.
Then try on a live or lab grown specimen and note effectiveness. Repeat the cycle, and with every success, push to more realistic forms of testing until it reaches human trials.
Many drugs that reach the last stage - human trials - often end up being used for something completely other than what they were designed for! One example of that is minoxidil - designed to regular blood pressure, used for regrowing hair!
chaos_emergent|15 days ago