[greygoo222]

You shouldn't so offhandedly assume a hunter-gatherer lifestyle couldn't lead to issues like increased risk of CRC, or that activities which lead to increased risk of CRC couldn't be what hunter-gatherers did. Evolution is neither fast nor perfectly precise. Plenty of animal populations have common health problems that simply weren't harmful enough to reproduction to be selected out, much less something rare and late-onset like CRC.

[inglor_cz]

I don't assume anything. From what we know about health of the last surviving hunter-gatherers, they suffer significantly less from "diseases of civilization" when taken in proportion to their settled neighbours. Some of those diseases (such as high blood pressure or diabetes 2nd type) seem to be totally absent in them. Cancers do happen, but not as often.

This pattern is quite old. Already ancient Egyptians suffered from civilizational diseases much more than hunter-gatherers, especially the richer ones (heart attacks, gout, cancer).

[greygoo222]

I won't bother checking or disputing the accuracy of your factual claims, because it does not matter.

Colorectal cancer is not the same thing as high blood pressure, or type 2 diabetes, or any other cancer that isn't colorectal cancer. Diseases are not a monolith and you cannot assume low risk of some diseases means low risk of others. That is wild guesswork passed off as logic, like measuring the shadow your testicles cast on the wall and announcing it is 24.1 degrees Celsius. Ultra-marathon runners also have low risk of type 2 diabetes!

Do you have specific evidence that modern hunter-gatherers have low rates of colorectal cancer that cannot be explained by survivorship bias, screening, genetic differences, and all other confounders, and that they are representative of historical hunter-gatherers? No? Then you cannot confidently conclude that hunter-gatherers didn't experience elevated rates of CRC.