[mystifyingpoi]

> How will you maintain multiple deployments across multiple regions in the world? Backups, security patches will start to take a toll

The same way as always - by automating the crap out of it.

> How granular is the right split? Not every country has a cloud provider.

Doesn't have to be one deployment for one country, does it? Having like 3 or 4 deployments across the globe already gives you (at least) 3-4 hours of inactivity window, let's say 1 am - 4 am or something.