[ahazred8ta]

[testing positive for the disease but it's not progressing] -- Yes, exactly this. There are people with two copies of the bad APOE4 gene. 95% of them develop early-onset Alzheimer's in their 50s. The medical community is now very intensely studying the remaining 5% to find out what's causing them to NOT get sick.

[RiverStone]

Can you provide the source for the 95% figure?

[ahazred8ta]

Sloppy wording. -- Fortea (2024) -- Over 95% of people with two copies have amyloid beta in their cerebrospinal fluid. (not full-blown Alzheimers symptoms, just early detection)

https://www.theguardian.com/society/article/2024/may/06/scie...