[john-radio]

the ergonomic advantage of left-to-right is that most players use right-handed guitars, so the guitar's cord comes out the right side of your body, and it's most ergonomic for it to be directed straight away from you to the right side of your pedal board, not criss-crossing in front of you towards the left side of your board.

[dmurray]

And Hendrix played the guitar left-handed, so the other way made more sense for him.

[xcf_seetan]

>criss-crossing in front of you towards the left side of your board. No need to criss-cross the cable in front of you, you can connect the cable to the guitar on the right side and the cable will go behind you and emerge on the left side, into the pedal board/fx processor.