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Scientists Inject Human Brain Cells Into Mice, Make Them Smarter

71 points| olalonde | 13 years ago |singularityhub.com

57 comments

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[+] tokenadult|13 years ago|reply
Typical of Singularity Hub, this is a link-baity treatment of a story that has already been widely reported. The underlying research study

http://www.cell.com/cell-stem-cell/abstract/S1934-5909(13)00...

is interesting, and worth replicating with varied experimental conditions, and indeed it may be important for clearing up what glia cells do in the human brain. But in terms of treatments on human beings, this looks a lot more radical and a lot more likely to be expensive and subject to regulation than simply engaging in deliberate practice and finding a good coach.

[+] dualogy|13 years ago|reply
Do we really want smarter rodents?

(Then again, think if we could secretly outsource loads of PHP SQL-CRUD projects to them..)

[+] xradionut|13 years ago|reply
They might get some of the bad human traits. Consider religious wars over brands of cheese or colors of automotive electrical wires.
[+] Nyubis|13 years ago|reply
This is a good question. HGTG-scenarios aside, what if they become sentient? Do they deserve the same moral weight humans have now?
[+] terhechte|13 years ago|reply
I for one welcome our new rodent overlords.
[+] wslh|13 years ago|reply
You don't know if they are already posting in HN now :-) singularity is near....
[+] brador|13 years ago|reply
Imagine if you could grow yourself a huge brain. I'm finding more and more that the biggest bottleneck in my awesome plans is me.

Or maybe you could grow a second brain and switch them out while one sleeps/defrags.

[+] cpursley|13 years ago|reply
What are we doing tonight, Brain?

The same thing we do every night, Pinky...

...Try and take over the world!

[+] ptbello|13 years ago|reply
oh and by the way, one of the mice is called Algernon

http://en.wikipedia.org/wiki/Flowers_for_Algernon#Short_stor...

[+] dsowers|13 years ago|reply
Just finished that book last night. It was a good read, but deeply unsettling for some strange reason. His intelligence decline at the end makes the reader feel like retardation is a very near threat to all of us. It's one of those threats that seems worse than death, too.
[+] exodust|13 years ago|reply
Perhaps the injected mice had less appetite from side effects of the human brain cells, therefore not crazy about the idea of getting hurt for food. Mice are already smart. They can steal and transport cat food in their mouths and stash it for later out of sight. That's not the actions of a stupid mouse.
[+] felix|13 years ago|reply
I know how this movie ends...

with the whole colony trying to get to the lee of the stone.

[+] nsns|13 years ago|reply
This title could be nicely used as a mirror for personal prejudice. If you manage to see through the lazy dust of anthropocentrism, you'll read it as full of horror and pain.
[+] quasque|13 years ago|reply
Every species favours its own - humans are not special in that regard.
[+] 2510c39011c5|13 years ago|reply
Could they inject human brain cells into dogs, instead of mice? I just feel a dog who knows English would be more lovely than a mouse who knows the same language...
[+] barbs|13 years ago|reply
"...and human’s are the smartest of all thinkers"

:|

[+] heydenberk|13 years ago|reply
Christine O'Donnell, 2010 Tea Party candidate for the senate in Delaware, totally saw this coming.
[+] systematical|13 years ago|reply
Sign me up for a shot of Einstein astrocytes.
[+] antsam|13 years ago|reply
I for one welcome our new mouse overlords.
[+] alexvr|13 years ago|reply
I bet they named the mouse Algernon.
[+] knodi|13 years ago|reply
Playing with fire.
[+] shadowrunner|13 years ago|reply
These experiments are cruel. Who has the right to experiment on these animals? Who gave these "scientists" permission to inflict suffering on these mice? Accountability and compassion are lacking here.

When will we as a race start challenging the morality of animal experimentation and vivisection? There needs to be protections afforded to animals. This cruelty needs to stop.

[+] benesch|13 years ago|reply
Turn the question on its head. Why is it right to prolong human and animal suffering to minimize the suffering of a few lab animals?

These experiments are incredibly important for science and healthcare.

[+] reasonattlm|13 years ago|reply
http://www.fightaging.org/archives/2010/04/animal-studies-in...

"Animal experimentation is horrible and terrible. Even in the most ethical of studies suffering is inflicted upon animals that otherwise would not have happened; entire genotypes of animals doomed to additional suffering have been bred in some cases. But the alternative is far worse: to not perform these animal studies, or rather for some privileged group to use force to prevent others from performing such studies, and so bring progress in medicine to a grinding halt. Without animal studies there would be no new meaningful advances in medical science. It is a harsh and unpleasant aspect of the human condition that forcing suffering upon animals in the course of scientific studies is necessary to advance both human and veterinary medicine. A few suffer for the benefit of many - an equation that should make any sane and compassionate person uncomfortable.

"Animal studies are even required to refine the science needed to move beyond animal studies. Ethics and morality aside, studies employing animals are expensive and time-consuming. Given the choice, scientists would much rather experiment on cells in a dish, or on slabs of unfeeling cultured tissue, or upon simulations of animals, if these methods would generate results of the same quality.

"In comparison to what might be and what is possible, we live in a barbaric age of suffering, war, death, and sundry other horrors that we like to keep behind the curtains and out of the mind's eye. But barbaric as it is, this age is far better than the past by all such measures. We no longer absolutely, definitely need to slaughter animals for food to sustain the populace, for example, and rates of violence between humans are far lower than in the pre-modern era of tribes and universal poverty. The option stands open today for a society of vegetarians: it is practical from a technological and economic standpoint. That we have not moved rapidly in that direction is our shame, and our descendants will look back on us as savages for this and many other reasons.

"Those people who criticize and take action against the use of animals in medical research should first look to their diets, and then to the practice of farming animals. Vast and expansive animal suffering is caused in the name of putting meat into the marketplace - greater many times over each month than in all the animal experiments in modern history. Persuade the omnivores of the human race to relinquish their participation in the meat market before savaging the medical science that will benefit both man and beast.

"In short, the human condition is a rotted, cloying swamp, but we're closer to the edge than we were - no longer up to our necks in it, we now have the luxury of finding more of our surroundings to be disgusting and primitive. The way out to solid ground is forward, through more of the same, until our biotechnology becomes good enough to do away with the suffering we must inflict upon animals in order to build better medicine. Perhaps along the way, societies will arise whose members also reject the needless suffering we presently choose to inflict upon animals in order to eat the same diet as our ancestors."

[+] quasque|13 years ago|reply
The animals were bred specifically for such experiments. For example, the mice in these experiments were blind, immunosuppressed mice that would not survive in the wild anyway. Such research is not done with cruelty in mind; the animals are taken care of as well as possible despite their eventual fate - even their deaths are performed quickly and painlessly. In laboratory jargon, they are termed "sacrifices" which I think very positively describes their role - their lives being taken for the greater good of knowledge, enlightenment, and the overall reduction of suffering.
[+] pixl97|13 years ago|reply
If they don't stop torturing these poor animals, we're going to hunt them down and lock them in cages!

That's the problem with reality, might really does make right.