[unalone]

Of course you can. Don't be daft.

There are plenty of advantages to relative sizing, and in general it's a good policy, but there are many excellently-designed web sites whose sizes are absolute – just as there are many shit designs that're responsive as hell.

[kaoD]

Eveytime I open a website with absolute sizes I want to cry. Most of my monitors have either crappy or too big resolutions.