[edj]

Link to the abstract on PubMed: http://www.ncbi.nlm.nih.gov/pubmed/24582957

Original is behind a paywall.

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I'd take all this with a grain of salt, though. The biology of aging is incredibly complex. Seemingly certain answers to the question of what causes or mediates aging (e.g. free radicals) have turned out to be less conclusive and all-explaining than researchers originally thought.

[stcredzero]

There are seven distinct mechanisms for cellular and intracellular damage resulting from aging. Improving the regulation of mitochondria could completely fix one and slow down the rate of accumulation of a few other types of damage, but that's it.

http://en.wikipedia.org/wiki/Strategies_for_Engineered_Negli...

[pyduan]

Please note that Aubrey de Grey's theories are highly controversial and while some of these mechanisms are indeed big topics in the field, many biogerontologists have been publicly skeptical of his claims. In fact, some of these are even mentioned in your link.

The way you worded it, it seems you're implying SENS is a widely accepted theory, while in fact it's anything but (although I'd say it certainly is interesting and worthy of investigation).