[bnr]

I'd love an adblocker with a blacklist instead of whitelist so I could keep the ads on for the long tail of my browsing and remove them only on sites that go overboard.

[maxerickson]

Just remove the default block lists. I do this with adblock+, only adding rules for things that I decide are obnoxious (mostly trackers).

[nkantar]

Could you somehow whitelist all domains and go from there?

Not on a computer right now to try it out for myself, but it sounds like an interesting approach.