Thomvis's comments

Thomvis | 9 months ago | on: Childhood leukemia: how a deadly cancer became treatable

My daughter died of AML earlier this year. AML is unfortunately much harder to treat than ALL. She was treated for almost three years (it came back twice). We "lived" with her in the hospital for around 1,5 years over that three year period.

Many of the chemo medications she got have been a stable of AML treatment for decades. From what I understood from our doctors, the improvement in survival rate for AML has come from supportive care, i.e. the ability to keep the patient alive during treatment. Treatment of bacterial and fungal infections has gotten a lot better.

AML is a very heterogeneous disease. The treatment depends a lot on the specific mutations the patient has. Research can only focus on so many target mutations at a time. We did see the progress over the three years we were there. I have high hopes that children with the same mutation as my daughter will in the near future have better chances, specifically thanks to menin inhibitors.

Thomvis | 5 years ago | on: Ask HN: Who is hiring? (January 2021)

Highstreet Mobile Retail | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time

We're looking for Backend, iOS & Android Engineers. Our mission with Highstreet is to connect people to the brands they love. We are a team of makers and we've built a native app SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS and that app constantly gets better.

- Backend Engineer: design and develop the Highstreet API, the beating heart of our product. Stack: Ruby / Sinatra / Minitest / Redis / OpenAPI / PostgreSQL / Go / Kubernetes / GCP / Gitlab CI. Contact the back-end lead directly at [email protected].

- iOS/Android Engineer: work on the native core library that powers our 25+ native apps. We use RxSwift/RxJava, SwiftUI, Kotlin, Dagger. Contact the mobile lead directly at [email protected].

More info: https://jobs.highstreetmobile.com

Thomvis | 5 years ago | on: Ask HN: Who is hiring? (September 2020)

Highstreet Mobile | Android Engineer | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time | https://www.highstreetmobile.com

Highstreet Mobile's mission is to connect people to the brands they love. We are a team of makers and we've built a SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS that we constantly refine and extend.

You'll be joining the team that is responsible for the core library that powers our Android apps. The core library provides all app capabilities, from API calls to UI, but can be extended to meet customer needs. We care deeply about the user experience and you'll be working closely with the design team when implementing new features and improvements. Our automated unit tests and extensive code reviews make sure code quality remains up to par.

Technologies we use: Kotlin / Java / RxJava / Dagger / OkHttp / Glide

Apply via the following link or contact me at [email protected] if you’d like to know more: https://jobs.highstreetmobile.com/android-engineer/en

Thomvis | 5 years ago | on: Ask HN: Who is hiring? (July 2020)

Highstreet Mobile | Android Engineer | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time | https://www.highstreetmobile.com

Highstreet Mobile's mission is to connect people to the brands they love. We are a team of makers and we've built a SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS that we constantly refine and extend.

You'll be joining the team that is responsible for the core library that powers our Android apps. The core library provides all app capabilities, from API calls to UI, but can be extended to meet customer needs. We care deeply about the user experience and you'll be working closely with the design team when implementing new features and improvements. Our automated unit tests and extensive code reviews make sure code quality remains up to par.

Technologies we use: Kotlin / Java / RxJava / Dagger / OkHttp / Glide

Apply via the following link or contact me at [email protected] if you’d like to know more: https://jobs.highstreetmobile.com/android-engineer/en

Thomvis | 5 years ago | on: Ask HN: Who is hiring? (June 2020)

Highstreet Mobile | Android Engineer | Utrecht (near Amsterdam), The Netherlands | Onsite/Remote (EU) | Full Time | https://jobs.highstreetmobile.com/android-engineer/en Highstreet Mobile's mission is to connect people to the brands they love. We are a team of makers and we've built a SaaS product for fashion brands. We enable brands to give an amazing shopping experience to their customers. Our customers get a native mobile shopping app for Android and iOS that we constantly refine and extend.

You'll be joining the team that is responsible for the core library that powers our Android apps. The core library provides all app capabilities, from API calls to UI, but can be extended to meet customer needs. We care deeply about the user experience and you'll be working closely with the design team when implementing new features and improvements. Our automated unit tests and extensive code reviews make sure code quality remains up to par.

Technologies we use: Kotlin / Java / RxJava / Dagger / OkHttp / Glide

Apply via the link above or contact me at [email protected] if you’d like to know more.

https://jobs.highstreetmobile.com/android-engineer/en

Thomvis | 8 years ago | on: Ask HN: Who is hiring? (April 2018)

Highstreet | iOS Engineer | Utrecht, The Netherlands | Onsite

We're building a native app platform that powers retail apps for brands around the world. We're a small team of engineers in a growing company (~15 people in total), focussed on building innovative apps with an excellent user experience and that deliver business to our customers.

We're looking for iOS Engineers with experience in creating well-architected mobile apps that offer a great user experience. When you come work with us, your first code is guaranteed to ship within two weeks. We care about our process to ensure bugs are caught, in your code and mine. We have a shared sense of responsibility throughout the company to keep complexity to a minimum and care about code quality. We're not just building for the now, we're in it for the long run.

About the company: https://www.highstreetmobile.com

About the job opening & apply at: https://highstreet-mobile-retail.homerun.co/ios-engineer/en

About me: I'm the lead mobile developer, working with the iOS & Android teams. Happy to answer any questions!

Thomvis | 9 years ago | on: Ask HN: Who is hiring? (April 2017)

Highstreet | Ruby Developer | Utrecht, The Netherlands | ONSITE | https://www.highstreetapp.com

At Highstreet, we build a platform for native mobile shopping apps that end-users love and delivers business to our customers, which are mostly fashion brands from all around the globe.

We are looking for a full-time back-end developer, who is excited to innovate mobile shopping. Would you like to build a robust, scalable platform that serves data to our apps around the globe. You will be joining our small but smart team with a start-up attitude. There is plenty of room for your ideas and initiatives on how to improve our platform.

I lead the iOS and Android teams at Highstreet and would love to talk to you if you're interested! Our interview process consists of a phone screening, in person/Skype interview, take-home assignment and a discussion in person/over Skype of the assignment.

More information and instructions on how to apply can be found on https://highstreet-mobile-retail.homerun.co/ruby-developer/e....

Thomvis | 12 years ago | on: Blendle – iTunes for journalism launches in the Netherlands

I think Blendle is doing a great job regarding reducing friction. I signed up and read my first article through the service yesterday within one minute after somebody in my Twitter feed shared it. The per-article fee is subtracted from my account as I read, but I can ask money back if I didn't like the article.

Thomvis | 13 years ago | on: What they don't tell you about being a game developer

In my own experience, it is not only about starting simple, but also finishing it simple. I know you're not saying it isn't, but what I want to emphasize is that it is too easy to say that you're done with something simple and then move on to the next/bigger thing. For example, what eru suggested, if you build a Tetris-like game. You probably can have the gameplay finished in a few hours. And then, move on? Or spend another week on polishing, menu's, sound, graphics, copy, etc. I think the most valuable part of the lesson of starting simple is in finishing it. (And they don't tell you that.)

Thomvis | 13 years ago | on: Is language unique to humans?

Regarding Sources for Neurological Studies: this paper [1] by Michael Arbib explores the neural and functional grounding of language skills in humans and their ancestors.

[1] Michael A. Arbib, From monkey-like action recognition to human language: An evolutionary framework for neurolinguistics, Behavioral and brain sciences 28, 2005, pp. 105-124. PDF: http://users.ecs.soton.ac.uk/harnad/Temp/arbib-bbs.pdf

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