krob
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1 year ago
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on: Type 2 diabetes: New treatment eliminates insulin for 86% of patients
Dr. Fung basically said that beta cell death is likely related to fatty deposits on the pancreas. So there is a fatty liver/pancreas cycle that requires a significant time duration of fasting. Eventually beta cells continue to produce normal amounts of insulin. T2D is not a death sentence, it just requires motivation from the patients and up-to-date knowledge of the treatment physician.
krob
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2 years ago
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on: Launch HN: Certainly Health (YC S23) – Book doctors without surprise bills
Years ago, back in like 2011, I worked for pricedoc.com, this was our primary goal as well. Doctors wouldn't talk to us. Legally they're bound to not due to their insurance contracts. The only doctors we gained some traction with were plastic surgery, and dental. Because these doctors tend to deal more with cash patients. We didn't survive long. Maybe 14 months. Then sold our IP to some other startup called greatvets.com and we struggled like crazy to get exposure by vets to want to use our product. Same goal to provide cash prices. Good luck.
krob
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2 years ago
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on: Slim people have a genetic advantage when it comes to maintaining their weight
Excessive sweet food causes insulin resistance, which makes your body flood with insulin for even the smallest amount of sugar, it makes you constantly store fat over using it for energy, it's partially why you get food coma from eating a subway sandwich. Soybean oil may play a role in causing mutations in our gene expression making our systems run less ideally.
https://www.sciencedaily.com/releases/2020/01/200117080827.h...
krob
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2 years ago
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on: Slim people have a genetic advantage when it comes to maintaining their weight
CI/CO is ideal circumstances, just like falling from the sky, computing how long it takes to hit the ground is not as simple as it's 9.8ms/s^2*m, you have to build a differential equation that accounts for all the various force factors involved. Our biology are those various force factors playing on the rate of incorporation of the energy and how the system which consumes energy may alter pathways, and this is where we run into permutations of the metabolism that are not accounted for by CI/CO. We know that people with metabolic syndrome and insulin resistance cannot loose weight because their hyper sensitive to any amount of sugar, so insulin causes them to constantly store energy, but some people who eat a lot of calories get a massive energy boost like they almost got some caffeine in their system. Our biology has millions of biological permutations that ideal systems cannot account for.
krob
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4 years ago
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on: I Quit Shopify After Five Months
Years of experience is relative to the company, and software type. Companies like Google, production products are likely on a totally different level than almost any other product in existence. So 10yrs at none google company is not equal to Google engineering. What plays into all of this is the complexity of the problems they solve at scale, and level of academic sophistication. Map software, search engines, Google app suite gui products are not simple or easy to build.
krob
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4 years ago
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on: All Those 23andMe Spit Tests Were Part of a Bigger Plan
Gain of function? You realize that mother nature is far more sophisticated than us humans. She has manufactured many plagues over the eons. we will likely never come up with viruses that have the kind of crazy cascading systemic building block chaos causing destruction in the human body. Radiation doesn't count because we just figured out we could harness it, but we have very little control over that. Viruses make ionic radiation look like child's play as just like ionizing radiation, studying the thing could kill you within days/weeks/months. You have a voodoo science belief that Dr Evil might create the next real zombie, only @9pm on Fox.
krob
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4 years ago
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on: How PHP Opcache Works
krob
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4 years ago
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on: Climate change: IPCC report is 'code red for humanity'
Not sure which country you live in, but if you can get a speed queen branded washer / dryer, you'll likely never have to replace them. They're repairable.
krob
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4 years ago
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on: FBI and Detroit police groomed 14 year old informant for years before conviction
Ugh, this is fucked up. Hope he gets lots of money $(10)^N, N=8 to 9 is okay in my book.
krob
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5 years ago
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on: US Senators call on FCC to raise broadband definition to 100Mbs down and up
my fiancee, her family. lives in Mecca, Ca, not too far from indio, ca, which is where the Cochella festival is, and they can only get ATT ADSL2, they get 6mbit/1.5mbit and it's a joke. using even tmobile 4g only gets you 10mbit for a few seconds via bursting speeds.
krob
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5 years ago
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on: Popular flea collar linked to almost 1700 pet deaths. EPA has issued no warning
I've had many cats in my lifetime. All the ones I had which we used flee collars eventually died of some breast tumor/ liver/kidney failure early in life around 5 cats died under 5 to 6yrs. We eventually stopped treating fleas, we just washed them, and sprayed our home, it was a much smarter solution. our last batch of 4 siamese all lived into their late teens, having never been given flea products.
krob
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5 years ago
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on: What's New in PHP 8.1
I don't agree with this. I'm not going to get into a holy war, but I soundly disagree that it's inferior. Any C/C++/Java programmer can become productive with php very rapidly. The callstacks are familiar to programmers, the language continues to get faster & faster as older legacy structures are replaced with smarter data-structures allowing for JIT optimizations.
krob
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5 years ago
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on: What's New in PHP 8.1
Dev recruitment is hard to find php developers? wtf are you smoking? I think a lot of this is highly dependent on where you are. My guess is you mostly deal with non php languages?
krob
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5 years ago
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on: Once the disease of gluttonous aristocrats, gout is now tormenting the masses
Gout is a metabolic disorder period. Excessive sugar in barley syrups from alcohol, and soda pop, and even excessive amount of starch in diet lead to metabolic purine synthesis. The metabolites produce purines in the process of storing away all this sugar, additionally causing inflation in the body the more your BMI is excessive. loose weight and the flair ups reduce, the numbers might not change. Been dealing with gout since I was 28, but had symptoms since around 23. Also have super flat feet making things worse. I take 300mg of allopurinol every day.
krob
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5 years ago
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on: Is a billion dollars worth of server lying on the ground?
what you're paying for is the capability of scalable architecture, on-demand launch, and heavy redundancy. this very easily acts as a multiplying cost factor and building out your own infrastructure as opposed to leveraging one that can dynamically scale as your needs require. Yes you can get away with paying for your own infrastructure at a third the cost, but then when you compute the cost of all the individual requirements. colocation ISP prices, space, people to manage all of these machines, the software to then scale yourself in equivalence, you eventually end up at w similar cost apples to apples, oranges to oranges if you replicate for yourself exactly what you get through AWS.
krob
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5 years ago
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on: YouTube-dl has received a DMCA takedown from RIAA
I think that they should update the readme and rebase the history and eliminate any references to the original copyrighted material of the readme file. possibly even making a request of GitHub to help them clean the repo or evidence of any logging information with regard to the copyrighted content. I think it would be relatively easy to argue that a web browser would be guilty of every single little thing that can be done through YouTube DL binary in the right hands. The only copyrightable information that YouTube - DL offers is an instruction set or a direct correlation to the fact that they can use this tool to do some things that are implicitly prohibited.
krob
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5 years ago
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on: The KDE community is moving to GitLab
I think it's a mistake for them to leave phabricator. This product is quite easy to get ci/cd going on. There are apis to submit back to tickets. it's highly customizable. Also the damn system never breaks; even when you think it broke. Git pull and run the migration tool. boom. Its a PHP system after all. Probably one of the most well written and methodical codebases out there. Also the community fixes bugs regularly, especially if they're simple and easy to replicate.
krob
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5 years ago
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on: Winamp’s woes: How the greatest MP3 player undid itself (2012)
thank you for building such a nice player. Can this use jackd?; for low latency audio playback.
krob
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5 years ago
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on: If a MacBook Pro runs hot or shows high kernel CPU, try charging it on the right
krob
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6 years ago
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on: First Maine inmate enrolled in graduate school conducts research in prison
this is one of those old biblical sayings, one who bites off their nose to spite their face. The face who is given to them out of the goodness of someone's heart if done through the process of enriching society with their work, I guess we'll be damned if they've helped the public let everyone die so we can punish that one person.
Revenge never improve the lives of anyone besides providing a momentary moment of peace, but society can be vengeful as well when you eliminate a brain who could improve the lives of others. This conundrum exists everywhere. Every religion, every person on the planet has seen this happen.
