svsaraf's comments

Hi folks - author here! Happy to answer any questions about the post, hopefully it's useful for folks following in Palantir's footsteps.

Ryan! Good to hear from you. I enjoyed this comment - I suppose early / late is relative. Palantir was founded in 2003 after all.

Hi folks - author here, happy to answer any questions!

Hi folks - author here. Happy to answer any questions about the post!

I only just realized that "Muff" "Invoice" may have a different meaning in the UK...

I know you're asking about developer tools - the main ones I use include:

* Webflow (in case the client needs something relatively unsophisticated)

* Django / HTMX / AlpineJS / Django Ninja (in case the client needs a full CRUD application with more powerful capabilities).

I also want to shamelessly plug - if you are looking to do freelance or contract work, and you want an easy way to manage the contract, engagements, milestones, and invoices, consider using withpartly.com.

I'm the founder and CEO, and looking for freelancers / contractors to play around with the alpha product (for free).

If you do opensource it, happy to help maintain it. This product would be helpful for my (fledgling) company, but would need to be self-hosted (use case is esignatures)

SEEKING FREELANCER | Remote USA

I'm creating software to make it easy for freelancers to manage their engagements, get paid, and handle all of the pieces of paper involved in that (NDA, IP assignment, etc). As part of that, I'm working with companies looking to hire contractors, specifically software engineers.

If you're looking to work with Series A / B companies as a software engineer for at least 10 hours a week (either in contract to hire or in permanent freelancer setups), please reach out! The main cost to you is you'll have to use my software and give me feedback on it. Thanks!

Email: [email protected]

Where is the Moneyball for knowledge workers?

You are out of date. CRISPR is extremely effective in live patients, usually packaged in a virus or lipid nano particle.

While CRISPR is often used in cultured cells (eg for CAR T therapies) there are CRISPR therapeutics in live human patients today in phase 3 trials for sickle cell disease (among other indications).

(I’m the author)

This is an underrated comment. These are good threads to pull on in future posts - thanks.

(I wrote the article)

Thanks for this comment - I think the economic point is spot on. I think the fear of losing control is a fair summary - unfortunately there is some evidence of a selection effect that might mean employers do have something to fear. https://www.fractional.work/p/showing-face-is-more-important...

For those of you who feel this solution is a bit too complex for your workflow, there are a couple of lightweight alternatives, including Sudopoint (https://www.sudopoint.com) which lets you specify what you need and download a CSV, in and out in a few seconds.

To the Synth team, awesome product! Great to see that more tools are getting built to help testing / QA workflows. I think this a huge area for the future. Welcome to the competition. :)

[Disclaimer] I'm the (solo, bootstrapped) founder of Sudopoint

There wouldn't have been time. Compartment syndrome is a medical emergency.

Do you mind discussing how you did the fuzzy matching?

My initial guess would've been dynamic programming (levenstein distance), but if this is API-wide, did you make a suffix tree?

It isn't true. Insulin was discovered in the early 1900s, but before it was used, starvation would extend the lifespan post-diagnosis from weeks to months, if that. After that, the patient would die of starvation.

Logging into innocentive lets you see more details about each challenge.

EDIT: To your second point: Even though it's 300 kg total, it looks like that's allocated to 2 75 kg objects and 6 25 kg objects. I would assume that means much less weight/space per unit to work with, given the dead weight to go along with it.

> Because of the high density of tungsten, it is unlikely that payload concepts may be proposed that identically match the characteristics of the MSL BMDs. To maximize the potential for innovative concepts while still achieving the desired spacecraft EDL performance, NASA is requesting that proposed concepts target 90% of the original MSL BMD mass while matching the volumetric dimensions used for MSL.

Still, I agree with you. It's a very difficult target.

I think the author addressed your concern:

> Ask journal editors and scientific peers to review study designs and analysis plans and commit to publish the results if the study is conducted and reported in a professional manner (which will be ensured by a second round of peer review).

If the study design is peer reviewed, I would hazard a guess that there would be less bad science, not more. Currently study design takes second priority to significant results, which is perhaps why we have the problems of inconsistent research in the first place.

Believe it or not, I'm not criticizing the study. It certainly has weaknesses, but I agree with its conclusion and its general methodology.

I'm criticizing Time magazine for making the claim that salt has no effect on blood pressure (or implying it), which is demonstrably not true.

My point is: if you're healthy, no, it isn't surprising that your body can regulate salt intake. If you aren't, it isn't surprising that doctors will want to keep track of how much salt you're eating.

> For a med STUDENT you show quite a lot arrogance.

I wish you hadn't said this, because I think it's unnecessary and diminishes the rest of your comment.