thisisnotmyname's comments

thisisnotmyname | 12 years ago | on: Ask HN: Who is hiring? (August 2013)

Codified Genomics - Houston TX codifiedgenomics.com

Codified Genomics is hiring a user interface and HCI developer. We have a massive amount of data to show users and need someone to develop new ways of presenting and interacting with it. Our current user interfaces are written in GWT, so experience with Java and css are important.

The software you write at Codified will directly influence healthcare decisions for thousands of patients. We do clinical genomic variant analysis. We take whole-exome sequence data and predict clinical outcome for the variants we observe in patients, which is then used by clinicians to inform treatment. To do this, we aggregate large amounts of additional data on individual genes and variants, and apply a series of proprietary algorithms.

A willingness to learn is more important to us than a Biology background, but the job will require you to become familiar with the Biology that we're working with.

Send resumes / portfolios to [email protected]

thisisnotmyname | 12 years ago | on: Ask HN: Who is hiring? (July 2013)

Codified Genomics - Houston TX (remote OK) codifiedgenomics.com

Software you write at Codified will directly influence healthcare decisions for thousands of patients. We're looking for experienced software engineers who are up to that challenge, and who have a track record of working in an environment that demands a high level of quality.

We do clinical genomic variant analysis. We take whole exome sequence data and predict clinical outcome for the variants we observe in patients, which is then used by clinicians to inform treatment. To do this, we aggregate large amounts of additional data on individual genes and variants, and apply a series of proprietary algorithms. We started with seed funding and are currently profitable with revenue from our first customer.

We're hiring our first engineer. At Codified your responsibilities will be wide - you will probably end up touching every piece of software we write, with an emphasis on the user facing applications. We are currently using GWT and mysql with some scripting in Python. Additionally, you'll help us grow our team over the next few months as we continue to add engineers.

We have a large number of interesting projects under active development, spanning natural language processing, machine learning, user interface design and of course sequence analysis.

We're looking for someone who is experienced, flexible and willing to work outside of their comfort zone. A willingness to learn is more important to us than a Biology background, but the job will require you to learn the basics of the Biology that we're working with.

We're willing to consider remote work for experienced candidates, but preference will be shown to candidates in the Houston area.

We are offering 70k+ salary and equity. Contact us at [email protected]

thisisnotmyname | 13 years ago | on: Telomerase – Mouse lifespan extended up to 24% with single treatment (May 2012)

Interfering with telomere activity is a critical step for cancer progression (see the halmarks of cancer, limitless reproductive potential), so this procedure essentially makes every cell in your body pre-cancerous.

In my opinion, the most amazing part about this is that the way in which telomerase is delivered is via a retrovirus, typically a relative of HIV.

thisisnotmyname | 13 years ago | on: Why we Die

I'd encourage a different interpretation of the data: Cancer holding steady actually is an improvement.

Everyone is guaranteed to die of something, and the longer you live the likelihood of that something being cancer greatly increases. So as people shift away from other categories, i.e. heart disease and childbirth, and live longer, they're going to shift towards the cancer category. I'm actually amazed that cancer hasn't gone up significantly.

thisisnotmyname | 13 years ago | on: How I Built a Self-adaptive System

From the description, this sounds quite over-engineered. You need a system to queue jobs and to automatically restart jobs that fail? I must be missing something here, can you help me figure out what it is?

thisisnotmyname | 14 years ago | on: New Normal: Majority Of Unemployed Attended College

This should be the top comment. This article seems to be playing games with the numbers. Why do they choose to focus on the fraction of the unemployed? This trend could just be explained by greater numbers of people attending some amount of college relative to the past. They should really show the fraction of college educated unemployed, vs fraction without college educated unemployed, but that wouldn't fit their narrative.

thisisnotmyname | 14 years ago | on: The Future of Science

"The norms don’t encourage the sharing of an interactive, full-color, 3 dimensional model of the protein, even if that would be a more suitable media format for the kind of knowledge that is being shared."

This is simply wrong - when you solve a protein structure is is mandatory that you submit it to the pdb (i.e http://www.pdb.org/pdb/101/motm.do?momID=148) and nearly every journal I read has both color figures and extensive online supplementary materials.

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