vsef's comments

vsef | 3 years ago | on: For many widows, the hardest part is mealtime (2019)

Easily mitigated by what? Doing less things with your partner seems to be your suggestion?

I am active with close friends that I have maintained for even longer! I am lucky enough to continue having close friends of 25 years I still do things with (including skiing).

The idea that my friends and activities mitigates this problem is absurd and I think shows how little you understand.

vsef | 3 years ago | on: For many widows, the hardest part is mealtime (2019)

This is such a lazy, bad take.

I was deeply moved by the article thinking about my own relationship of twenty years, and imagining the inevitable death of one of us in the future.

Much of my own pain would involve activities you suggest while giving advice about something you don't understand.

I immediately thought about how my ski routine would be a trigger like this for me. I ski near 100 days a year. My first thought reading the article was how much I would hurt making morning coffee and breakfast without my husband and not talking and making ski plans for the day. And how hard and long it would be for that break in daily routine to no longer be a constant reminder of absence. All the harder by it's very routineness and connection to something that is otherwise very pleasurable to me.

That this type of pain would be mitigated by "getting out there and doing fun stuff and having more friends and not pleasure eating" is a perspective with zero understanding of what the bond in a decades long marriage is like or why meal time is so emotionally salient.

vsef | 3 years ago | on: New Psychedelic Entactogens

Mescaline is a substituted amphetamine just like MDMA. As is the antidepressant buproprion (Wellbutrin). And a variety of very strong hallucinogens.

vsef | 3 years ago | on: Stop Drinking Now

GHB is a great alcohol substitute in many ways but also has an extremely unforgiving dose response curve with doses that can't be safely eyeballed and that build up in unpredictable ways over successive dosings. The lethal to effective dose ratio is worse than for alcohol, with doses that are much smaller and easier to accidentally ingest. Almost all regular users will have overshot the mark and knocked themselves out at some point, the edge for this level of mild overdose is much lower and sharper than for alcohol.

It is safer than alcohol in terms of properly dosed effects, but it has many safety drawbacks in terms of using safely in public social settings the way alcohol is used.

It's not just regulatory difficulties with it as an alcohol substitute.

vsef | 3 years ago

This essay is very long. While it does accurately touch on high risk activities (multiple partners, anal sex, sex clubs) it is primarily a deep dive into the author's wildly neurotic relationship to sex and his total misunderstanding of what is normal or common. His specific medical problems towards the end are extremely not normal, yikes.

vsef | 4 years ago | on: Scientists say they can read nearly the whole genome of an IVF-created embryo

Some people do choose to have deaf children: https://jme.bmj.com/content/28/5/283

There was quite a bit of outrage around that case from hearing people, but it seems no different than two parents with genetic deafness choosing each other and then not trying to use genetic testing/embryo selection to have a hearing baby.

I do think when this type of genetic manipulation becomes possible/mainstream there will be many traits chosen by parents that aren't considered universally desirable.

vsef | 4 years ago | on: Highly virulent HIV variant found to be circulating in Europe for decades

The viruses listed by parent aren't spread sexually, though they are all herpes viruses.

EBV is also known as HSV-4 and gets to 60% plus prevalence in children, 90% in US adults. If there are populations with especially low prevalence I'm not aware of it.

HSV-1 which causes mouth cold sores is present in 50-80% of people, also easily acquired in childhood. Only 20-40% of infected people get cold sores so most infected people don't realize they have it.

Chicken pox/shingles is also a type of herpes virus with well known massive prevalence!

Genital herpes is just one of many types of herpes viruses that affect humans.

vsef | 4 years ago

There is no such thing as a trace/undetectable transmission. These studies have been going on a long time now with large numbers of participants, replicated in multiple countries/different populations. The results are very strong and not based on measuring viral levels.

vsef | 4 years ago | on: Activision Blizzard pushes out dozens of employees over workplace misconduct

It is a cultural problem but the game industry is not SV based. Blizzard Activision is SoCal, Ubisoft is French (with studios in many locations). I worked at a studio owned by Activision (in SoCal) in the early 2000s and the culture was certainly toxic.

I just find it funny how often commenters here assume all broism originates in SV.

vsef | 4 years ago

Absolutely, we form such weird attachments to things we saw as kids that we don't really remember well at all.

ST:TOS I highly recommend because it remains engaging/entertaining and is fascinating to see as a lens into the late 60s, but "good" it is not.

ST:TNG I love and I think is the better show but it shocked me too when I tried to rewatch in order after ST:TOS. The first seasons are not great! I really had erased a lot of it from my memory. I realize now that it's not until a couple seasons in that it became the show I remember, that show was lucky to hang in there long enough to hit its stride.

vsef | 4 years ago

I just finished a rewatch of Star Trek the original series and wow professionals working together to do their job is... So not what that show is. I don't like Discovery but TOS is absolutely people acting emotional and unprofessionally in basically every single episode. It is hilarious.

Watching TOS in full was very eye opening to how much current cultural memory of what that show was doesn't match what was actually in the show.

vsef | 4 years ago | on: Japan’s curiously quiescent inflation rate

The quote originally is about Japan and Argentina being outliers in development trajectory, Japan extremely rapidly developing after WW2 to one of the world's richest countries vs Argentina's decline from being one of the world's richest countries after WW1. Argentina stands apart in having been initially on similar track as the "developed" rich countries and then significantly deteriorated.

vsef | 4 years ago | on: US wildfires have killed nearly 20% of world’s giant sequoias in two years

You've misunderstood, from your own article:

“California’s forests naturally adapted to low-intensity fire, nature’s preferred management tool, but Gold Rush-era clearcutting followed by a wholesale policy of fire suppression resulted in the overly dense, ailing forests that dominate the landscape today.”

It doesn't say 20 million acres need to be removed, it says that's the area that needs burned. Low intensity fire clears fuels without killing mature trees, this is especially true for long lived redwood species that expect fire to clear out smaller vegetation below them. It's not about removal or clear cutting.

vsef | 4 years ago | on: Antiviral Molnupiravir Reduces Risk of Hospitalization/Death by ~50 Percent

There are quite a few nucleoside analogues that have been used for HIV treatment: AZT, Zerit, FTC, Videx, Abacavir, 3TC, Hivid. There may be others I'm missing.

Of these, only Abacavir and FTC (as part of Truvada) are still used, the others have fallen out of use or are no longer even manufactured due to their bad side effect profiles and propensity for severe adverse reactions. 'Nuke-sparing' regimen planning specifically would combine other classes of drugs to avoid this class due to side effect issues.

I think it's great to have this new treatment option but this class of medications is well known for its side effects. Avoiding vaccines as 'unproven' and then going for this in particular I would consider eye rollingly wrong headed.

vsef | 4 years ago | on: Confessions of a Michelin Star Inspector

Well Le Cinq in particular had a scandalously bad (and very entertaining) review from a very well known restaurant critic questioning how the hell it had 3 stars: https://www.google.com/amp/s/amp.theguardian.com/lifeandstyl...

So maybe trust your gut more?

I've only ever eaten at one restaurant with one star (Hisop in Barcelona) and it was wonderful, but I don't think there's any reason to think the Michelin ratings are a perfect system.

vsef | 4 years ago | on: Where the Gay Things Are

To respond to everything in this that I found either intellectually or personally offensive would be exhausting.

Gay marriage doesn't fit neatly into left/right ideological politics and the author's core complaint is that the supporters of gay marriage aren't sufficiently leftist.

The claim that the only people benefitting from the overturn of doma were/are the wealthy is patently absurd and factually false. The claim that the push for marriage caused harm by diverting resources from community health causes is also ridiculous. The disregard for gay families with children is palpable.

The core argument is no different than an extreme conservative libertarian argument that gay marriage shouldn't be supported because marriage shouldn't be the concern of the state. The near or medium term possibility of a socialist or libertarian utopia us zero. The harms of lack of access to the social institutions that do exist are real. Describing gaining access to those existing social structures as actively harmful because it doesn't suit your hard left ideology is gross.

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